LRGP: Reaction and Process Engineering Laboratory (C. Frochot)


Reaction and Process Engineering Laboratory, LRGP, UMR 7274 CNRS-University of Lorraine, 1 rue Grandville, 54000 Nancy, France



Porphyrin synthesis / targeting / time-resolved spectroscopy / singlet oxygen detection / photodynamic therapy

5 Recent Publications (last two years)

  1. “Titania And Silica Nanoparticles Coupled To Chlorin e6 For Anti-Cancer Photodynamic Therapy” Youssef Z., Jouan-Hureaux V., Colombeau L., Arnoux P., Moussaron A., Baros F., Toufaily J., Hamieh T., Roques-Carmes T., Frochot C., Photodiagnosis and Photodynamic Therapy, 2018, 22, 115-126.
  2. “New Photodynamic Molecular Beacons as cancer-targeted agents in PDT” Stallivieri A., Colombeau L., Devy J., Etique N., Chaintreuil C., MyrzakhmetovB., Achard M., Baros F., Arnoux P., Vanderesse R., Frochot C.,  Bioorg. Med. Chem., 2018, 26(3), 688-702 .
  3. “Ultrasmall AGuIX Theranostic Nanoparticles for Vascular-Targeted Interstitial Photodynamic Therapy of Glioblastoma” Thomas E., Colombeau L., Gries M., Peterlini T., Mathieu C., Thomas N., Boura C., Frochot C., Vanderesse R., Lux F., Barberi-Heyob M., Tillement O.,  International Journal of Nanomedicine, 2017, 12, 7075-7088.
  4.  “Synthesis of mono-, di- and triporphyrin building blocks by click chemistry for photodynamic therapy application” Modh Gazzali A., Colombeau L., Arnoux P., Wahab H. A., Frochot C., Vanderesse R., Acherar S.,  Tetrahedron 2107, 73(5) 532-541
  5. “Folic acid conjugates with photosensitizer for cancer targeting in photodynamic therapy: synthesis and photophysical properties” Stallivieri A.,Colombeau L., Jetpisbayeva DG.,Moussaron A., Myrzakhmetov B., Arnoux P., Acherar S., Vanderesse R., Frochot C.,  Bioorg. Med. Chem. 2017, 25, 1-10.

Group Members in MAPYRO

C. Frochot (

P. Arnoux (

F. Baros (francis.baros@univ-lorraine.)

S. Acherar ( )